遗传基因分析 - Agena Bioscience

Targeted genetic insight for inherited conditions

The MassARRAY^® System and Agena Bioscience’s iPlex Pro^® chemistry enable laboratories to efficiently analyze known variants associated with hereditary genetic conditions using a flexible, cost-effective workflow. Both the CFTR 100+ Panel and the HFE Genotyping Panel are optimized for precise variant discrimination in a scalable format.

CFTR 100+ Panel – Expanded CFTR variant coverage aligned with updated recommendations from leading societies
HFE Genotyping Panel – Targeted detection of common variants associated with hereditary hemochromatosis
Custom Genotyping Assays – Flexible assay development to support laboratory-specific hereditary genetics targets

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Proven Performance for Confident CFTR Detection

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CFTR LEARNING CENTER

Why Expanded, Guideline-Aligned CFTR Panels Matter

The CFTR gene encodes the cystic fibrosis transmembrane conductance regulator, a chloride channel expressed in epithelial cells of the lungs, pancreas, gastrointestinal tract, sweat glands, and reproductive system. Proper CFTR function regulates salt and water transport across cell membranes. When pathogenic variants disrupt this function, thickened secretions accumulate, leading to the multi-system manifestations of cystic fibrosis (CF).⁴

Cystic fibrosis is one of the most common autosomal recessive genetic conditions in individuals of Northern European ancestry, with a prevalence of approximately 1 in 2,500–3,300 live births, though it affects individuals across all genetic ancestries.²